Open-source software unlocks rapid DNA structure generation and analysis in one workflow

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

DNA repair enzyme uses one-dimensional sliding to detect key sites, researchers reveal

DNA is the blueprint of the human body. However, tens of thousands of DNA lesions occur in our bodies every day. In ...
Nanowerk

Improved design rules enable faster, higher-yield DNA origami assembly

New insights into DNA assembly could streamline the design and manufacturing of nanostructures for medicine, materials and ...
GitHub

Chiron3D: an interpretable deep learning framework for understanding the DNA code of chromatin looping

Chiron3D is a DNA-only deep learning model that predicts cell-type–specific CTCF HiChIP contact maps from 524,288 bp genomic windows. The model uses a frozen Borzoi backbone with lightweight adapters ...