Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...
Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...
Since its inception, spatial biology has proven a revolutionary frontier in life science research. However, there is still plenty of room for growth in the systems we use to conduct spatial biology ...
A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...
Despite progress in cancer biology, deciphering the spatial architecture of the tumor microenvironment remains a challenge. Traditional approaches lack the resolution to map cell-type-specific gene ...
A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold ...
A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche ...
Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation ... | Cell And Molecular Biology ...
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